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Dioscin Suppresses Prostate Cancer Stemness and Induces Apoptosis via Inhibition of the EGFR/STAT3 Signaling Pathway

Yi Hyun Choi, Hong Lae Kim, Hye Jin Jung

Prostate cancer stem cells (PCSCs) are increasingly recognized as the primary drivers of therapeutic resistance in advanced prostate cancer, establishing them a...

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DOI: https://doi.org/10.22889/KJP.2026.57.3.149

Stress Resistant Effect of Scopoletin from Artemisia capillaris Thunb. in Caenorhabditis elegans

Yeong Jee Kim, Jun Hyeong Kim, Dae Keun Kim

In the search for anti-aging compounds in native Korean plants, scopoletin isolated from Thunb. (Compositae) was shown in experiments using the model system t...

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DOI: https://doi.org/10.22889/KJP.2026.57.3.158

Triterpenoid Derivatives from the Twigs of Stephanandra incisa

Jeong-Yeon Kang, Yongsoo Kwon, Heejung Yang

Eight triterpenoid compounds were isolated from the 80% methanol extract of the twigs of (Thunb.). Based on spectroscopic and physicochemical analyses, the iso...

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DOI: https://doi.org/10.22889/KJP.2026.57.3.165

Antibacterial Activity and Attenuation of Bacteria-Induced Inflammatory Effects of Methanol Extract of Salvia miltiorrhiza against the Periodontal Pathogen Aggregatibacter actinomycetemcomitans

Jeong Hyeon Lim, Sungsook Choi

() is a gram-negative oral pathogen, whose virulence relies on Cdt toxin, bofilm formation and outer membrane protein. This study evaluated a comprehensive eff...

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DOI: https://doi.org/10.22889/KJP.2026.57.3.172

Validation of a Simultaneous Determination of 10 Red and Yellow Synthetic Dyes Using HPLC-PDA in Herbal Medicines

Soobin Song, Jinchul Kim, Seong Mi Lee, InYeong Hwang, Jonghwan Kim, Kyu-Heon Kim, Jinhee Hwang, Jiyeon Kim

The adulteration of herbal medicines with synthetic colorants to enhance marketability has been reported, and concerns regarding such practices persist. Althoug...

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DOI: https://doi.org/10.22889/KJP.2026.57.3.182

Optimization of Extraction Conditions for Platycodin D-Related Compounds from Platycodon grandiflorus Roots Using Box-Behnken Design-Based Response Surface Methodology

Seong-Joon Cho, Dong-Min Kang, Woo-Jin Jeong, Yu Bin Lee, Sang Eun Lee, Yun-Suk Kim, Mi Kyeong Lee, Mi-Jeong Ahn

This study investigated the effects of extraction conditions on platycodin D, D, and D from the roots of Platycodon grandiflorus, and predicted optimal extracti...

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DOI: https://doi.org/10.22889/KJP.2026.57.3.194

Development and Validation of an HPLC-DAD Method for the Simultaneous Quantification of Scopoletin and Chicoric Acid in SPB-206

Soo-Yeon Ahn, Seon-Hee Kim, Kee Dong Yoon

SPB-206 is being developed as an anti-obesity functional ingredient and is prepared by mixing hot-water extracts of L. and H. Dahlstedt. In this study, we dev...

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DOI: https://doi.org/10.22889/KJP.2026.57.3.204