Current Issue

Bioactive Marine Macroalgae for Mitigating Health Risks Associated with Particulate Matter and Microplastics: A Review

Ju-Young Ko, Bok Yun Kang, Min-Ho Oak, Hyun Jung Kim

Recently, particulate matter (PM) and micro-/nanoplastics (MP/NP) have emerged as significant environmental risk factors that disrupt molecular homeostasis in t...

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DOI: https://doi.org/10.22889/KJP.2026.57.1.1

Genkwanin Facilitates Long-term Potentiation via Calcium-permeable AMPA Receptor in the Hippocampus

Changmin Kim, Somin Moon, Dong Hyun Kim

Mild cognitive impairment (MCI) is regarded as a prodromal stage of Alzheimer’s disease (AD), and enhancing cognitive function during this period is a crucial s...

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DOI: https://doi.org/10.22889/KJP.2026.57.1.18

Neuroprotective Activity of Clematis mandshurica

Jinbae Won, Choong Je Ma

Oxidative stress is widely recognized as a central driver in the progression of neurodegenerative diseases, where it contributes to neuronal apoptosis through d...

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DOI: https://doi.org/10.22889/KJP.2026.57.1.24

Anti-inflammatory Effects of Carex kobomugi in RAW 264.7 Cells

Seungyeon Kim, Yewon Kim, Seojin Ryu, Seojeong Ahn, Suyeon Yeo, Seeun Lee, Hyeonji Jeon, Damin Jeong, Hyobin Jeong, Joonghyun Shim

This study aimed to evaluate the anti-inflammatory effects of extract on skin, using the RAW 264.7 macrophage cell line. The anti-inflammatory effects of extr...

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DOI: https://doi.org/10.22889/KJP.2026.57.1.31

Effects of Methanol Extract of Cratoxylum formosum (Jack) Benth. & Hook.f. ex Dyer Stem on Acetylcholinesterase Activity and Amyloid Precursor Protein metabolism in Neuronal Cells

Ga Eun Han, Ha Yeon Choi, Gyeong Min Lee, Ju Eun Kim, Bounleuane Douangdeuane, Jae Yoon Leem

(Jack) Benth. & Hook.f. ex Dyer has been traditionally used in Asia to treat wounds, fever, cough, and food poisoning. This study aimed to evaluate the inhibit...

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DOI: https://doi.org/10.22889/KJP.2026.57.1.38

Neuroprotective and Antioxidant Effect of Cheongwisan Against Glutamate-induced Excitotoxicity

Mihyun Jeong, Hye Jin Yang, Malk Eun Pak

Oxidative stress contributes to neuronal damage and neurodegenerative disease as Alzheimer’s disease (AD). While glutamate, a key neurotransmitter in the centra...

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DOI: https://doi.org/10.22889/KJP.2026.57.1.47

Antioxidant Effect of Methylene chloride Fraction of the Guzeunggupo-processed Curcuma longa L. in Caenorhabditis elegans

Ji Woo Choi, Nam Jin Ju, Jun Hyeong Kim, Hyo Jung Kim, Dae Keun Kim

In the process of searching for antioxidants in plants, the methylene chloride fraction of guzeungupo-processed L. was observed to have a strong scavenging eff...

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DOI: https://doi.org/10.22889/KJP.2026.57.1.54

Integrated Network Pharmacology and Molecular Docking Analysis to Elucidate the Multi-Target Mechanism of Betulin in Cognitive Enhancement

Choong Je Ma

Betulin has been reported to exhibit neuroprotective and memory-enhancing effects, but its underlying molecular mechanisms remain incompletely understood. AI-as...

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DOI: https://doi.org/10.22889/KJP.2026.57.1.60

Lucidenic Acid A-rich Antler-shaped Ganoderma lucidum Extract Enhances Skin Barrier and Suppresses Staphylococcus aureus Infection

Ye-Lin Kim, Kyung-Baeg Roh, Kyungeun Jeon, Dehun Ryu, Youngsu Jang, Eunae Cho, Deokhoon Park, Eunsun Jung

This study was conducted to evaluate the skin barrier enhancing effects and the potential to alleviate –associated skin disorders of an antler-shaped extract (...

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DOI: https://doi.org/10.22889/KJP.2026.57.1.71

HPLC-Analytical Validation for the Analysis of Major Components in Eremochloa ophiuroides (Munro) Hack. Extract

Ji-Su Mun, Seong-Hee Kang, Chang-Won Kang, Hyun-Jun Choi, Eun-Mi Lee

This study aimed to develop and validate a high-performance liquid chromatography (HPLC) method for the quantitative analysis of maysin, a major bioactive flavo...

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DOI: https://doi.org/10.22889/KJP.2026.57.1.80